Studies on Antiulcer Drugs. I. Synthesis and Antiulcer Activities of Imidazo(1,2-a)pyridinyl-2-oxobenzoxazolidines-3-oxo-2H-1,4-benzoxazines and Related Compounds.

synthesis of 3-aryl-2h-benzo[b]-1,4-oxazines in [omim]bf4 and reduction of organic compounds in methylimidazolium formate

در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...

Actions of antiulcer drugs.

Antidiarrhoeal and Antiulcer Activities of Mammea Africana

The   stembark of Mammea africana is used traditionally for the treatment of stomach pains. The present study was designed to evaluate the effects of ethanolic stembark extract of Mammea africana on experimentally induced diarrhoea and ulcer . The extract ( 30 – 90mg/kg) was administered orally in rats 30 minutes to one hour before the induction of diarrhoeal and ulcer using di...

Phenoxypropylamines: synthesis and antiulcer evaluation.

We have synthesized a number of phenoxypropylamines from N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}chloroacetamide (3). All the products have been characterized by elemental analysis, (1)H-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity results, we found that two of themshowed significant gastric acid antisecretory activity.

antidiarrhoeal and antiulcer activities of mammea africana

the   stembark of mammea africana is used traditionally for the treatment of stomach pains. the present study was designed to evaluate the effects of ethanolic stembark extract of mammea africana on experimentally induced diarrhoea and ulcer . the extract ( 30 – 90mg/kg) was administered orally in rats 30 minutes to one hour before the induction of diarrhoeal and ulcer using different experimen...